Sleep is something that has really been an unexplored topic cross-culturally.
在各种文化中,睡眠是一个未被探索的话题。
With (the gap between) the church's teachings and ways of thinking being eclipsed by the Renaissance, the gap between the medieval and modern periods had been bridged, leading to new and unexplored intellectual territories.
There appear to be many unexplored matters about the motivation to reflect—for example, the value of externally motivated reflection as opposed to that of teachers who might reflect by habit.